Synonyms | NAC1 |
Swiss Prot Num | Q96RE7 |
Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human BTBD14B. |
Product Type | Antibodies |
Storage | Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
References | 1. akayama,K., Cancer Res. 67 (17), 8058-8064 (2007). 2. avidson,B., Hum. Pathol. 38 (7), 1030-1036 (2007). 3. akayama,K., Proc. Natl. Acad. Sci. U.S.A. 103 (49), 18739-18744 (2006). |
|
Format | State: Liquid Ig fraction |
? | Purification: Pepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
? | Buffer System: PBS with 0.09% (W/V) sodium azide |
|
Specificity | This antibody detects Nac1 (BTBD14B) at center. |
Add. information | Molecular weight: 57258 Da |
Application | ELISA 1:1,000. Immunohistochemistry 1:10 - 1:50. |
Background | BTBD14B functions as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. In humans this protein is upregulated in a number of carcinomas and is localized in discrete nuclear bodies that correlate with tumour recurrence. |
Concentration | 0.25 mg/ml |