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Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-24-374872 |
AP13993PU-N |
NAE1//Human/Rabbit |
1/EA |
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¹®ÀÇ |
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Subject
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NAE1 |
Description
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/ Human/Rabbit |
Clonality
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Mono |
Company
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Acris Antibodies GmbH |
Application
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Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot |
Conjugation
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Immunogen
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Contents
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Description: Manufacturer | Acris Antibodies GmbH | Quantity | 0.1 mg | Reactivity | Human | Presentation | Purified | Applications | Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot | Isotype | Ig | Host | Rabbit | PDF datasheet | view | Shipping to | Worldwide | Synonyms | APPBP1, HPP1 | Swiss Prot Num | Q13564 | Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human APPBP1. | Product Type | Antibodies | Storage | Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. | References | 1. Chen,Y., J. Cell Biol. 163 (1), 27-33 (2003). 2. Chen,Y., J. Neurochem. 85 (3), 801-809 (2003). 3. Walden,H., Nature 422 (6929), 330-334 (2003). 4. Chow,N., J. Biol. Chem. 271 (19), 11339-11346 (1996). | |
Format | State: Liquid Ig fraction | ? | Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. | ? | Buffer System: PBS with 0.09% (W/V) sodium azide | |
Specificity | This antibody detects NAE1 (APPBP1) at C-term. | Add. information | Molecular weight: 60252 Da | Application | ELISA 1:1,000. Western blot 1:50 - 1:100. Immunohistochemistry 1:50 - 1:100. | Background | APPBP1 binds to the beta-amyloid precursor protein, a cell surface protein with signal-transducing properties thought to play a role in the pathogenesis of Alzheimer's disease. In addition, this protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. APPB1 is required for cell cycle progression through the S/M checkpoint. | Concentration | 0.25 mg/ml | |
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