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| Cat. No |
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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-24-374874 |
AP13995PU-N |
NAE1//Human/Rabbit |
1/EA |
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문의 |
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Subject
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NAE1 |
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Description
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/ Human/Rabbit |
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Clonality
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Mono |
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Company
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Acris Antibodies GmbH |
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Application
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Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot |
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Conjugation
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Immunogen
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Contents
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Description: | Manufacturer | Acris Antibodies GmbH | | Quantity | 0.1 mg | | Reactivity | Human | | Presentation | Purified | | Applications | Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot | | Isotype | Ig | | Host | Rabbit | | PDF datasheet | view | | Shipping to | Worldwide | | Synonyms | APPBP1, HPP1 | | Swiss Prot Num | Q13564 | | Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human APPBP1. | | Product Type | Antibodies | | Storage | Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. | | References | 1. Chen,Y., J. Cell Biol. 163 (1), 27-33 (2003). 2. Chen,Y., J. Neurochem. 85 (3), 801-809 (2003). 3. Walden,H., Nature 422 (6929), 330-334 (2003). 4. Chow,N., J. Biol. Chem. 271 (19), 11339-11346 (1996). | |
| Format | State: Liquid Ig fraction | | ? | Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. | | ? | Buffer System: PBS with 0.09% (W/V) sodium azide | |
| Specificity | This antibody detects APPBP1 at N-term. | | Add. information | Molecular weight: 60252 Da | | Application | ELISA 1:1,000. Western blot 1:50 - 1:100. Immunohistochemistry 1:10 - 1:50. | | Background | APPBP1 binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, this protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. APPBP1 is required for cell cycle progression through the S/M checkpoint. | | Concentration | 0.25 mg/ml | |
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