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| Cat. No |
Model |
Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-24-374878 |
AP13086PU-N |
NAIP//Human/Rabbit |
1/EA |
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문의 |
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Subject
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NAIP |
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Description
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/ Human/Rabbit |
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Clonality
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Mono |
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Company
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Acris Antibodies GmbH |
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Application
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Enzyme Immunoassay |
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Conjugation
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Immunogen
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Contents
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Description: | Manufacturer | Acris Antibodies GmbH | | Quantity | 0.1 mg | | Reactivity | Human | | Presentation | Purified | | Applications | Enzyme Immunoassay | | Isotype | Ig | | Host | Rabbit | | PDF datasheet | view | | Shipping to | Worldwide | | Synonyms | BIRC1 | | Swiss Prot Num | Q13075 | | Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human BIRC1. | | Product Type | Antibodies | | Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. | | References | 1. Notarbartolo, M., et al., Leuk. Res. 26(9):857-862 (2002). 2. Monani, U.R., et al., Hum. Mol. Genet. 8(7):1177-1183 (1999). 3. Yamamoto, K., et al., Biochem. Biophys. Res. Commun. 264(3):998-1006 (1999). 4. Chen, Q., et al., Genomics 48(1):121-127 (1998). 5. Liston, P., et al., Nature 379(6563):349-353 (1996). | |
| Format | State: Liquid purified Ig | | ? | Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS | | ? | Buffer System: PBS with 0.09% (W/V) sodium azide | |
| Specificity | This antibody reacts to BIRC1. | | Application | ELISA: 1/1,000. | | Background | The gene coding for BIRC1 is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The BIRC1 protein contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. A second transcript for this gene has been described, but its full length nature has not been determined. | | Concentration | 0.25 mg/ml | |
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