Synonyms | NR4A1, GFRP1, HMR, NUR77, ST-59, N10 |
Swiss Prot Num | P22736 |
Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S351 of human NR4A1. |
Product Type | Antibodies |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
References | 1. Lu, L., et al., J. Clin. Endocrinol. Metab. 89(8):4113-4118 (2004). 2. Castro-Obregon, S., et al., J. Biol. Chem. 279(17):17543-17553 (2004). 3. Lin, B., et al., Cell 116(4):527-540 (2004). 4. Choi, J.W., et al., Cancer Res. 64(1):35-39 (2004). 5. Ye, X., et al., Int. J. Biochem. Cell Biol. 36(1):98-113 (2004). |
|
Format | State: Liquid purified Ig fraction. |
? | Purification: Protein A Chromatography followed by two-step phosphospecific peptide affinity purification. |
? | Buffer System: PBS with 0.09% (W/V) Sodium Azide as preservative. |
|
Specificity | This antibody detects NAK1/NR4A1 pSer351 . Predicted to cross react with Mouse (100% Antigen Homology). |
Add. information | Molecular weight: 64463 Da |
Application | ELISA: 1/1,000. Dot Blot: 1/100-1/500. |
Background | NR4A1 is a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. |
Caution | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Concentration | 0.25 mg/ml |