Synonyms | NR4A1, GFRP1, HMR, NUR77, ST-59, N10 |
Swiss Prot Num | P22736 |
Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S351 of human NR4A1. |
Product Type | Antibodies |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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Format | State: Liquid purified Ig |
? | Purification: Protein A column, followed by peptide affinity purification |
? | Buffer System: PBS with 0.09% (W/V) sodium azide |
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Specificity | This antibody reacts to NUR77 (NR4A1) pSer351. |
Application | ELISA: 1/1,000. Western blotting: 1/50 - 1/100. |
Background | NR4A1 is a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. This protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. |
Caution | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Concentration | 0.25 mg/ml |