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| Cat. No |
Model |
Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-24-374882 |
AP14010PU-N |
NALP2//Human/Rabbit |
1/EA |
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문의 |
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Subject
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NALP2 |
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Description
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/ Human/Rabbit |
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Clonality
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Mono |
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Company
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Acris Antibodies GmbH |
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Application
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Enzyme Immunoassay, Paraffin Sections |
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Conjugation
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Immunogen
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Contents
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Description: | Manufacturer | Acris Antibodies GmbH | | Quantity | 0.1 mg | | Reactivity | Human | | Presentation | Purified | | Applications | Enzyme Immunoassay, Paraffin Sections | | Isotype | Ig | | Host | Rabbit | | PDF datasheet | view | | Shipping to | Worldwide | | Synonyms | NLRP2, NBS1, PAN1, PYPAF2 | | Swiss Prot Num | P59046 | | Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human NALP12. | | Product Type | Antibodies | | Storage | Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. | | References | 1. Ye,Z., Mol. Cell. Biol. 28 (5), 1841-1850 (2008). 2. Jeru,I., Proc. Natl. Acad. Sci. U.S.A. 105 (5), 1614-1619 (2008). 3. Arthur,J.C., J. Immunol. 179 (9), 6291-6296 (2007). | |
| Format | State: Liquid Ig fraction | | ? | Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. | | ? | Buffer System: PBS with 0.09% (W/V) sodium azide | |
| Specificity | This antibody detects NALP12 at N-term. | | Add. information | Molecular weight: 120173 Da | | Application | ELISA 1:1,000. Immunohistochemistry 1:10 - 1:50. | | Background | NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP12, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes. | | Concentration | 0.25 mg/ml | |
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