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Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-24-374883 |
AP14011PU-N |
NALP2//Human/Rabbit |
1/EA |
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¹®ÀÇ |
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Subject
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NALP2 |
Description
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/ Human/Rabbit |
Clonality
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Mono |
Company
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Acris Antibodies GmbH |
Application
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Enzyme Immunoassay, Paraffin Sections |
Conjugation
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Immunogen
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Contents
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Description: Manufacturer | Acris Antibodies GmbH | Quantity | 0.1 mg | Reactivity | Human | Presentation | Purified | Applications | Enzyme Immunoassay, Paraffin Sections | Isotype | Ig | Host | Rabbit | PDF datasheet | view | Shipping to | Worldwide | Synonyms | NLRP2, NBS1, PAN1, PYPAF2 | Swiss Prot Num | P59046 | Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human NALP12. | Product Type | Antibodies | Storage | PBS with 0.09% (W/V) sodium azide | References | 1. Ye,Z., Mol. Cell. Biol. 28 (5), 1841-1850 (2008). 2. Jeru,I., Proc. Natl. Acad. Sci. U.S.A. 105 (5), 1614-1619 (2008). 3. Arthur,J.C., J. Immunol. 179 (9), 6291-6296 (2007). | |
Format | State: Liquid Ig fraction | ? | Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. | ? | Buffer System: PBS with 0.09% (W/V) sodium azide | |
Specificity | This antibody detects NALP12 at C-term. | Add. information | Molecular weight: 120173 Da | Application | ELISA 1:1,000. Immunohistochemistry 1:10 - 1:50. | Background | NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP12, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes. | Concentration | 0.25 mg/ml | |
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