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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-24-366868 |
AP08194PU-N |
14-3-3 protein beta/alpha//Human, Mouse, Rat/Rabbit |
1/EA |
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문의 |
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Subject
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14-3-3 protein beta/alpha |
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Description
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/ Human, Mouse, Rat/Rabbit |
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Clonality
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Mono |
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Company
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Acris Antibodies GmbH |
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Application
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Paraffin Sections, Western blot / Immunoblot |
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Conjugation
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Immunogen
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Contents
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Description: | Manufacturer | Acris Antibodies GmbH | | Quantity | 50 ug | | Reactivity | Human, Mouse, Rat | | Presentation | Aff - Purified | | Applications | Paraffin Sections, Western blot / Immunoblot | | Isotype | IgG | | Host | Rabbit | | PDF datasheet | view | | Shipping to | Not USA/Canada | | Synonyms | YWHAB, KCIP-1, Protein 1054, FocusOn116 | | Swiss Prot Num | P31946 | | Immunogen | Synthetic peptide corresponding to Peptide near the N-terminus of human YWHAB. | | Product Type | Antibodies | | Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. | |
| Format | State: Liquid purified Ig fraction. | | ? | Purification: Affinity Chromatography. | | ? | Buffer System: PBS, pH 7.4 containing 0.05% Sodium Azide as preservative and 0.2% BSA as stabilizer. | |
| Specificity | This antibody is specific to 14-3-3 protein beta/alpha. | | Application | Immunohistochemistry on Paraffin Sections: 10 µg/ml. Western Blot. | | Background | 14-3-3 alpha + beta mediate signal transduction by binding to phosphoserine containing proteins. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases. It may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. They are also adapter proteins implicated in the regulation of a large spectrum of both general and specialized signaling pathway. They bind to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. | | Concentration | 0.2 mg/ml | | Focuson | 116 Antibody Panel to Proteins of the 14-3-3 family (14-3-3 beta, 14-3-3 gamma, 14-3-3 epsilon, 14-3-3 zeta, 14-3-3 theta, 14-3-3 sigma, 14-3-3 eta) | |
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