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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-24-366893 |
AP15332PU-N |
14-3-3 protein zeta//Human, Mouse, Rat/Rabbit |
1/EA |
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문의 |
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Subject
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14-3-3 protein zeta |
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Description
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/ Human, Mouse, Rat/Rabbit |
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Clonality
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Mono |
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Company
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Acris Antibodies GmbH |
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Application
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Paraffin Sections, Western blot / Immunoblot |
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Conjugation
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Immunogen
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Contents
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Description: | Manufacturer | Acris Antibodies GmbH | | Quantity | 1.0 ml | | Reactivity | Human, Mouse, Rat | | Presentation | Purified | | Applications | Paraffin Sections, Western blot / Immunoblot | | Host | Rabbit | | PDF datasheet | view | | Shipping to | Worldwide | | Synonyms | YWHAZ, KCIP-1, FocusOn116 | | Swiss Prot Num | P63104 | | Immunogen | Synthetic peptide corresponding to aa 134-149 of human 14-3-3 zeta | | Product Type | Antibodies | | Storage | Store the antibody (undiluted) at 2 – 8 °C. Shelf life: One year from despatch. | |
| Format | State: Liquid affinity purified Ig fraction | | ? | Buffer System: 10 mM PBS, pH 7.4 with BSA and Sodium Azide | |
| Specificity | This antibody detects 14-3-3 protein zeta (aa 134-149). | | Add. information | Molecular weight: 30kDa Cellular localisation: Cytoplasmic | | Application | Western blot. Immunohistochemistry on paraffin sections (1:50, 30 min at RT); staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Positive control: NIH3T3 cells. Breast ca. | | Background | 14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 beta, gamma, theta, epsilon, zeta, sigma, and nu. 14-3-3 proteins function in broad regulation of these ligand proteins, by cytoplasmic sequestration, occupation of interaction domains and import/export sequences, prevention of degradation, activation/repression of enzyme activity etc. | | Concentration | 0.2 mg/ml | | Focuson | 116 Antibody Panel to Proteins of the 14-3-3 family (14-3-3 beta, 14-3-3 gamma, 14-3-3 epsilon, 14-3-3 zeta, 14-3-3 theta, 14-3-3 sigma, 14-3-3 eta) | |
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