| Synonyms | 4-1BB ligand, CD137L |
| Swiss Prot Num | P41274 |
| Immunogen | 41BBL-Fc Fusion Protein. |
| Product Type | Antibodies |
| Recommended Isotype Control | SM25P, SM25PX |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. Goodwin, R.G. et al. (1993) Molecular cloning of a ligand for the inducible T cell gene 4-1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor. Eur. J. Immunol. 23: 2631-41. |
|
| Format | State: Liquid purified IgG fraction. |
| ? | Purification: Affinity Chromatography on Protein G |
| ? | Buffer System: PBS, pH 7.4 containing 0.09% Sodium Azide as preservative. |
|
| Specificity | This antibody recognises 4-1BB Ligand (CD137L). |
| Application | Flow Cytometry (1/10-1/50): Use 10 ?l of the suggested working dilution to label 10e6 cells in 100 ?l. Immunoprecipitation. |
| Background | CD137L is a 50kD type 2 transmembrane protein, which is a member of the TNF superfamily. In mice CD137L is expressed on activated T-cells, B-cells, macrophages and dendritic cells. Interaction of CD137L with its receptor 4-1BB (CD137) is reported to be involved in T and B cell growth and T cell effector function. |
| Concentration | 1.0 mg/ml |
