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Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-23-351539 |
NBP1-02413 |
ADAMTS4 Antibody//Human/Rabbit |
1/EA |
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¹®ÀÇ |
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Subject
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ADAMTS4 Antibody |
Description
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/ Human/Rabbit |
Clonality
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Poly |
Company
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Novus biologicals |
Application
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IHC-P |
Conjugation
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Immunogen
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Contents
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Description:Summary: Species: | Hu | Applications: | IHC-P | Clonality: | Polyclonal | | Gene: | ADAMTS4 | Purity: | Immunogen affinity purified | Host: | Rabbit | | Specificity: | C-terminal domain of human ADAMTS4 | Details: Immunogen: | Synthetic peptide - KLH conjugated corresponding to C-terminal domain of human | Gene Symbol: ADAMTS4 Entrez: | 9507 (Human) | Swiss Prot: | O75173 (Human) | Related Genes: | ADAMTS2, ACAN, ADAMTS5, ADAMTS3, ADAMTS, MMP3, MMP13, MMP-13, ADAMTS1, VCAN, IL1B, ADAMTS-1, MMP9, TNF, TIMP-1, BCAN, MMP1, SLC25A12, IL6, TIMP1, MAPK1, TIMP3, NFKB1, OSM, MMP14, BMP1, TGFB1, ADAM-TS4, COMP, PTGS2, ADAMTS9, NOS2, FMOD, MAPK14, FURIN, ADAM-TS5, MMP17, MMP2, BMP7, PCSK6 | Background: ADAMTS4, also known as aggrecanase-1, is a Metallopeptidase M12B type protease that is responsible for degradation of the articular cartilage protein aggrecan and the brain extracellular matrix proteoglycan brevican. The ADAMTS4 protein contains a signal sequence, a propeptide domain, a catalytic domain, a disintegrin-like motif, and a C-terminal domain with a thrombospondin (TSP) type 1 motif. ADAMTS4 has been implicated in inflammatory joint diseases, and it also may be a factor in the progression of glioma and Alzheimer's disease. Species: Reactivity: | This antibody is reactive to Human. Rat ( Identity: 29 % Similarity: 41 %) | Applications: Uses: | This antibody is useful for the following applications and at the following dilutions: Immunohistochemistry-Paraffin 20 ug/ml | Dilutions: | Immunohistochemistry-Paraffin 20 ug/ml, | Concentrations: | 1.0 mg/ml | Packaging: Buffer: | PBS | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | Preservative: | 0.1% Sodium Azide | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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