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Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-24-375763 |
AP05657PU-N |
PPAR GAMMA//Human, Mouse, Rat, Canine, Guinea Pig, Duck, Hamst/Rabbit |
1/EA |
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문의 |
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Subject
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PPAR GAMMA |
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Description
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/ Human, Mouse, Rat, Canine, Guinea Pig, Duck, Hamst/Rabbit |
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Clonality
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Mono |
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Company
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Acris Antibodies GmbH |
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Application
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Enzyme Immunoassay |
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Conjugation
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Immunogen
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Contents
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Description: | Manufacturer | Acris Antibodies GmbH | | Quantity | 50 ug | | Reactivity | Human, Mouse, Rat, Canine, Guinea Pig, Duck, Hamster, Mink, Monkey, Rabbit | | Presentation | Purified | | Applications | Enzyme Immunoassay | | Isotype | IgG | | Host | Rabbit | | PDF datasheet | view | | Shipping to | Worldwide | | Synonyms | PPARG | | Swiss Prot Num | P37231 | | Immunogen | Synthetic peptide corresponding to amino acids 255 - 268 of human PPAR gamma isoform 1. | | Product Type | Antibodies | | Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. | | References | 1. Lazar, M.A. (2005) PPAR gamma, 10 years later. Biochimie. 87: 9 - 13. 2. Lehrke, M. and Lazar, M.A. (2005) The many faces of PPARgamma. Cell. 123: 993 - 999. | |
| Format | State: Liquid purified IgG | | ? | Buffer System: Phosphate buffered saline pH7.2 containing 0.01% Sodium Azide (NaN3) | |
| Specificity | This antibody detects human peroxisome proliferator-activated receptor gamma (PPARG). | | Application | ELISA: 1:8000 - 1:32000. | | Background | PPARG is a member of the nuclear hormone receptor subfamily of transcription factors. Upon activation, PPARG forms heterodimers with retinoid X receptors (RXRs), and functions to regulate transcription of specific gene sequences. PPARG is principally involved in the cellular assimilation of lipids, with key roles in adipocyte differentiation and adipogenesis. Two alternatively spliced isoforms of PPARG exist, termed PPARG1 and PPARG2, which are identical except for an additional 30 amino acids at the N-terminus of PPARG2. This results in a predominant adipocyte localisation for PPARG2, whilst PPARG1 is ubiquitously expressed. PPARG has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. | | Caution | (A full Health and Safety assessment is available upon request) This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only. | | Concentration | 1.0mg/ml | |
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