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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-24-366945 |
AP05779PU-N |
AADC / DDC//Human, Rat, Bovine, Canine, Guinea Pig, Rabbit, Sh/Sheep |
1/EA |
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문의 |
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Subject
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AADC / DDC |
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Description
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/ Human, Rat, Bovine, Canine, Guinea Pig, Rabbit, Sh/Sheep |
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Clonality
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Mono |
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Company
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Acris Antibodies GmbH |
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Application
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Western blot / Immunoblot |
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Conjugation
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Immunogen
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Contents
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Description: | Manufacturer | Acris Antibodies GmbH | | Quantity | 0.1 ml | | Reactivity | Human, Rat, Bovine, Canine, Guinea Pig, Rabbit, Sheep | | Presentation | Purified | | Applications | Western blot / Immunoblot | | Isotype | IgG | | Host | Sheep | | PDF datasheet | view | | Shipping to | Worldwide | | Synonyms | DOPA decarboxylase | | Swiss Prot Num | P20711 | | Immunogen | SDS denatured recombinant bovine DOPA Decarboxylase expressed in E. coli and purified from inclusion bodies. | | Product Type | Antibodies | | Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. | |
| Format | State: Liquid purified IgG | | ? | Buffer System: 10mM Hepes pH7.5, 150mM NaCl containing 0.09% Sodium Azide, 0.01% Bovine Serum Albumin, 50% Glycerol | |
| Specificity | This antibody recognises DOPA decarboxylase (aromatic-L-amino acid decarboxylase, DDC). | | Application | Western Blot: 1:1000; detects a band of approximately 55kDa in bovine adrenal medulla lysate. | | Background | DOPA decarboxylase is an enzyme that catalyses the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. The enzyme is expressed ubiquitously and is essential for the formation of catecholamines, indoleamines and trace amines. DDC is considered to be the rate-limiting step for the formation of trace amines, but not for the formation of catecholamines or indoleamines. It also becomes rate-limiting for dopamine formation in Parkinsons disease patients treated with LDOPA. | | Caution | (A full Health and Safety assessment is available upon request) This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only. | |
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