| Synonyms | AASS, Alpha-aminoadipic semialdehyde synthase, mitochondrial, LKR/SDH |
| Swiss Prot Num | Q9UDR5 |
| Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human AASS. |
| Product Type | Antibodies |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. Sacksteder,K.A., Am. J. Hum. Genet. 66 (6), 1736-1743 (2000) |
|
| Format | State: Liquid purified Ig fraction. |
| ? | Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| ? | Buffer System: PBS with 0.09% (W/V) Sodium Azide as preservative. |
|
| Specificity | This antibody detects AASS (Center). |
| Add. information | Molecular weight: 102001 Da |
| Application | ELISA: 1/1,000. Immunohistochemistry: 1/50-1/100. |
| Background | AASS is a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in the gene encoding this protein are associated with familial hyperlysinemia. |
| Caution | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Concentration | 0.25 mg/ml |
