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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-24-366984 |
AM00510PU-N |
ABCC7 / CFTR//Human, Mouse, Rat/Mouse |
1/EA |
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Subject
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ABCC7 / CFTR |
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Description
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/ Human, Mouse, Rat/Mouse |
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Clonality
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Mono |
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Company
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Acris Antibodies GmbH |
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Application
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Immunofluorescence, Western blot / Immunoblot, Immunoprecipitation |
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Conjugation
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Immunogen
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Contents
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Description: | Manufacturer | Acris Antibodies GmbH | | Quantity | 0.1 mg | | Reactivity | Human, Mouse, Rat | | Presentation | Purified | | Applications | Immunofluorescence, Western blot / Immunoblot, Immunoprecipitation | | Isotype | IgG1 | | Host | Mouse | | Clone | L12B4 | | PDF datasheet | view | | Shipping to | Not USA/Canada | | Synonyms | Cystic fibrosis transmembrane conductance regulator | | Swiss Prot Num | P13569 | | Immunogen | Recombinant protein encoding NBF1 domain of human CFTR. | | Product Type | Antibodies | | Recommended Isotype Control | SM10P (for use in human samples), SM20P (for use in rat samples), AM03095PU-N | |
| Immunogen | Swiss Prot Num: P13569 | | ? | Remarks: Mol. Wt. of Antigen: 165-170 kDa Epitope: aa 386-412. | | Storage | Store the antibody undiluted at 2-8°C for one month or in aliquots at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. | | References | 1. Kartner N. et al.. Nature Genetics 1:390, 321-327. 1992. | |
| Format | State: Liquid purified Ig fraction. | | ? | Purification: Protein G Chromatography. | | ? | Buffer System: 10 mM PBS, pH 7.4 containing 0.2% BSA as stabilizer and 0.09% Sodium Azide as preservative. | |
| Specificity | This antibody detects Cystic Fibrosis Transmembrane Regulator at aa 386-412 Cellular Localization: Cell membrane. | | Application | Immunofluorescence. Immunoprecipitation. (See Ref.1) Western Blotting. (See Ref.1) Positive Control: Pancreas. | | Background | CFTR (cystic fibrosis transmembrane conductance regulator) is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation. | | Concentration | 0.2 mg/ml | |
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