| Synonyms | C-C motif chemokine 22, ABCD-1, Scya22, Small-inducible cytokine A22 |
| Swiss Prot Num | O88430 |
| Product Type | Antibodies |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
|
| Format | State: Liquid purified Ig |
| ? | Purification: Affinity chromatography |
| ? | Buffer System: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. |
|
| Specificity | ABCD1 antibody detects endogenous levels of ABCD1 protein. |
| Application | ELISA: 1:40000~1:60000. WB: 1:500~1:1000. |
| Background | The MDC gene is one of several Cys-Cys (CC) cytokine genes which are clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by MDC displays chemotactic activity for natural killer cells, chronically activated T lymphocytes, monocytes and dendritic cells. It has no chemoattractant activity for eosinophils, neutrophils and resting T lymphocytes and also displays a mild activity for primary activated T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. |
| Concentration | 1,0 mg/ml |
