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| Cat. No |
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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-24-367009 |
AP15379PU-N |
ABL1//Human, Mouse/Rabbit |
1/EA |
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문의 |
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Subject
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ABL1 |
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Description
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/ Human, Mouse/Rabbit |
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Clonality
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Mono |
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Company
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Acris Antibodies GmbH |
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Application
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Paraffin Sections, Western blot / Immunoblot |
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Conjugation
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Immunogen
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Contents
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Description: | Manufacturer | Acris Antibodies GmbH | | Quantity | 1.0 ml | | Reactivity | Human, Mouse | | Presentation | Purified | | Applications | Paraffin Sections, Western blot / Immunoblot | | Host | Rabbit | | PDF datasheet | view | | Shipping to | Worldwide | | Synonyms | c-ABL, p150, JTK7 | | Swiss Prot Num | P00519 | | Immunogen | A synthetic peptide from the sequence adjacent to protein tyrosine kinase domain of human c-Abl. | | Product Type | Antibodies | | Storage | Store the antibody undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch. | |
| Format | State: Liquid purified Ig | | ? | Buffer System: 10mM PBS, pH 7.4 with BSA and Sodium Azide | |
| Specificity | This antibody reacts to ABL1. | | Application | Western Blotting. Immunoprecipitation. Immunohistochemistry on paraffin sections: 1/50 for 10 min at RT; Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Positive control: Placenta | | Background | The c-Abl proto-oncogene encodes a protein tyrosine kinase that is located in the cytoplasm and nucleus. In chronic myelogenous leukemia and in a subset of acute lymphoblastic leukemias, the c-Abl proto-oncogene undergoes a (9;22) chromosomal translocation producing a novel rearranged chromosome (the Philadelphia chromosome) As the result of the fusion of c-Abl sequences from chromosome 9 to the Bcr gene on chromosome 22. The molecular consequence of this translocation is the generation of a chimeric Bcr/Abl mRNA encoding activated Abl protein tyrosine kinase. | | Concentration | 0,2 mg/ml | |
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