| Synonyms | ABLL, ARG |
| Swiss Prot Num | P42684 |
| Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding Y251 of human ABL. |
| Product Type | Antibodies |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. Cao, C., et al., Biochemistry 42(35):10348-10353 (2003). 2. Cao, C., et al., J. Biol. Chem. 278(32):29667-29675 (2003). 3. Kruh, G.D., et al., Proc. Natl. Acad. Sci. U.S.A. 87(15):5802-5806 (1990). 4. Kruh, G.D., et al., Science 234(4783):1545-1548 (1986). 5. Bianchi, C., et al., FEBS Lett. 527 (1-3), 216-222 (2002). |
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| Format | State: Liquid purified Ig fraction. |
| ? | Purification: Protein A Chromatography followed by peptide affinity purification. |
| ? | Buffer System: PBS with 0.09% (W/V) Sodium Azide as preservative. |
|
| Specificity | This antibody detects ABL2. |
| Add. information | Molecular weight: 128343 Da |
| Application | ELISA: 1/1,000. Western Blot: 1/10-1/50. |
| Background | ABL2 is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells. The ABL2 gene product is expressed as two variants bearing different amino termini, both approximately 12-kb in length. The peptide used to generate this antibody is 100% conserved between ABL2 and ABL1. |
| Caution | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Concentration | 0.25 mg/ml |
