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| Cat. No |
Model |
Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-24-375172 |
AP13200PU-N |
OAS1 / OIAS//Human, Mouse/Rabbit |
1/EA |
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문의 |
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Subject
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OAS1 / OIAS |
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Description
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/ Human, Mouse/Rabbit |
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Clonality
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Mono |
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Company
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Acris Antibodies GmbH |
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Application
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Enzyme Immunoassay, Western blot / Immunoblot |
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Conjugation
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Immunogen
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Contents
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Description: | Manufacturer | Acris Antibodies GmbH | | Quantity | 0.1 mg | | Reactivity | Human, Mouse | | Presentation | Purified | | Applications | Enzyme Immunoassay, Western blot / Immunoblot | | Isotype | Ig | | Host | Rabbit | | PDF datasheet | view | | Shipping to | Worldwide | | Synonyms | 2'-5'-oligoadenylate synthetase 1, p46/p42 OAS | | Swiss Prot Num | P00973 | | Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected selected from the C-terminal region of human OAS1. | | Product Type | Antibodies | | Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. | | References | 1. Hongyan Wang, et al. J. Biol. Chem., Jun 2008; 283: 15845 - 15852. 2. Han, Jian-Qiu, et al. J. Virol. 2007 Jun 01;81(11):5561-5572. (Applications: WB) 3. Alimirah, Fatouma, et al. Mol. Cancer Res. 2007 Mar 01;5(3):251-259. (Applications: WB) 4. Anthony N. van den Pol, et al. J. Virol. 2007 Jan 01;81(1):332-348. (Applications: ICC) 5. Lee, Jongdae, et al. PNAS 2006 Feb 07;103(6):1828-1833. (Applications: WB) | |
| Format | State: Liquid purified Ig | | ? | Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS | | ? | Buffer System: PBS with 0.09% (W/V) sodium azide | |
| Specificity | This antibody reacts to OAS1. | | Application | ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/10 - 1/50. | | Background | OAS1 is an interferon inducible protein that may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. It binds double-stranded RNA and polymerizes ATP into PPP(A2'P5'A)N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. This protein is associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions. | | Caution | This product is for research use only. Not for use in diagnostic or therapeutic procedures. | | Concentration | 0.25 mg/ml | |
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