| Synonyms | B-FABP |
| Immunogen | A 17 amino acid peptide located near the centre of human FABP7. |
| Product Type | Antibodies |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. Goto, Y., et al. (2006) A new melanoma antigen fatty acidbinding protein 7, involved in proliferation and invasion, is a potential target for immunotherapy and molecular target therapy. Cancer Res.?¾ 66:4443 - 9. 2. Chmurzynska, A. (2006) The multigene family of fatty acidbinding proteins (FABPs): function, structure and polymorphism. J. Appl. Genet.?¾ 47:39 - 48. 3. Arai, Y., et al. (2005) Role of FABP7, a downstream gene of pax6, in the maintenance of neuroepithelial cells during early embryonic development of the rat cortex. J. Neurosci.?¾ 25:9752 - 61. 4. Shimizu, F., et al. (1997) Isolation and expression of a cDNA for human brain fatty acidbinding protein (BFABP). Biochim. Biophys. Acta?¾ 1354:24 - 28 |
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| Format | State: Liquid purified IgG |
| ? | Buffer System: Phosphate buffered saline containing 0.02% Sodium Azide (NaN3) |
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| Specificity | This antibody recognises Fatty acid binding protein 7 (FABP7), also known as Brain Fatty acid binding protein (B-FABP). |
| Application | Western Blot: 0.5 - 1.0?g/ml; detects a band of approximately 25kDa in human breast tissue cell lysates. |
| Background | FABP7 is a 15 kDa cytoplasmic protein belonging to the Fatty acid binding protein (FABP) family. The FABP family is a group of small highly conserved cytoplasmic proteins that bind long chain fatty acids and other hydrophobic ligands. Research suggests that FABPs are involved in fatty acid uptake, transport and metabolism. FABP7 is expressed in the brain and other neurological tissues. FABP7 is an important component in the establishment of the radial glial fiber system in the developing brain, a system that is required for the migration of immature neurones to establish cortical layers. Studies have also demonstrated that FABP7 is frequently expressed in melanomas. |
| Caution | (A full Health and Safety assessment is available upon request) This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only. |
| Concentration | 1.0mg/ml |
