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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-350975 |
NBP1-05037 |
ABCE1 Antibody//Bovine, Canine/Goat |
1/EA |
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Subject
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ABCE1 Antibody |
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Description
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/ Bovine, Canine/Goat |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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ELISA, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Rt, Mu, Hu, Ca, Bv | | Applications: | WB, ELISA | | Clonality: | Polyclonal | | | Gene: | ABCE1 | | Purity: | Immunogen affinity purified | | Host: | Goat | | | Specificity: | ABCE1 / RNase L | | Publications: | Antibody has not yet been mentioned in a publication. | Details: | Isotype: | IgG | | Immunogen: | Synthetic peptide, NHDKCKPKKCRQEC, representing the N-Terminus of the sequence according to NP_002931.2; NP_001035809.1 | | Epitope: | N-Terminus | Gene Symbol: ABCE1 | Entrez: | 6059 (Human) | | | 24015 (Mouse) | | | 361390 (Rat) | | Swiss Prot: | NP_002931.2; NP_001035809.1 (Human) | | Related Genes: | RNASEL, ABCC1, TNFSF10, ABCB5, ABCD3, ABCC4, ABCB1, ABCF1, MYOG, ABCF2, ABCB10, UBASH3A, ABCG2, ABCF3, ABCC3, ABCB6, ABCD4, ABCG1, ABCC2, EIF2AK2, PKLR, ABCA7, ABCD1, IBSP, CPOX, TGM1, ABCB4, PSMD12, MYOD1, SLC25A5, MARCKSL1, MDM4, FSCN1, TNFAIP3, TNFRSF1A, ELOF1, ARCN1, MSH3, PIK3R3, EXOSC10 | Background: **Please note, this product is one of a range of Investigative Grade antibodies, made against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues available to us. These antibodies are affinity purified using their peptide immunogen and are known to give low background staining in a western blot. However no additional claims are made for their ability to recognize native protein in any application. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq] Species: | Reactivity: | Human, Mouse, Rat, Dog and Cow. | Applications: | Uses: | This antibody is useful for Peptide ELISA and Western Blot. Preliminary experiments gave an approx. 80kDa band in Human Spleen lysates after 0.2?g/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 67.3kDa according to NP_002931.2. The ~80kDa band was successfully blocked by incubation with the immunizing peptide. | | Dilutions: | ELISA 1:32000, Western Blot 0.2?g/ml | | Concentrations: | 0.5 mg/ml | | Positive Controls: | 1 positive controls | Packaging: | Buffer: | Tris-saline [pH7.3] with 0.5% BSA | | Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. | | Preservative: | 0.02% Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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