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| Cat. No |
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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-350953 |
NBP1-30032 |
ABCA4 Antibody (3F4)//Bovine, Human/Mouse |
1/EA |
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문의 |
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Subject
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ABCA4 Antibody (3F4) |
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Description
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/ Bovine, Human/Mouse |
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Clonality
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Mono |
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Company
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Novus biologicals |
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Application
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IHC-P, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Xp, Mu, Hu, Bv | | Applications: | WB, IHC | | Clonality: | Monoclonal | | | Gene: | ABCA4 | | Purity: | protein G purified | | Host: | Mouse | | | Publications: | Antibody has been mentioned in at least 4 publications. | Details: | Clone: | 3F4 | | Isotype: | IgG | | Immunogen: | Partially purified bovine 220-kDa disc rim protein. | Gene Symbol: ABCA4 | Related Genes: | INS, ABCA1, EMB, ATP6V0A1, RFC2, RFC1, RFC4, LEP, RPGR, CRX, BEST1, TNFRSF17, KCNH2, DMD, ALB, ARCN1, ERG, APOA1, RPE, RHO, GGH, GH1, TNF, GNL3, SLC17A5, KRAS, RANGAP1, ENPEP, RP, ELOVL4, AMD1, ABCB1, LXR, FMOD, CFB, CAT, RIMS1, FEV, RBBP8, ADIPOQ | Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2. Species: | Reactivity: | Cross reacts with Bovine, Human, Mouse and Xenopus. | Applications: | Uses: | This antibody is useful in Western Blot and Immunohistochemistry. | | Dilutions: | immunohistochemistry 1:100, Western Blot 1:1000 | Packaging: | Buffer: | 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50% glycerol. | | Storage: | Store at -80C. Avoid freeze-thaw cycles. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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