|
| |
| Cat. No |
Model |
Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-350959 |
NB400-163G |
ABCA7 Antibody (7A1-144) [DyLight 488]//Mouse/Rat |
1/EA |
|
|
|
|
문의 |
|
|
|
|
|
|
|
Subject
|
ABCA7 Antibody (7A1-144) [DyLight 488] |
|
Description
|
/ Mouse/Rat |
|
Clonality
|
Mono |
|
Company
|
Novus biologicals |
|
Application
|
FACS, Western Blot |
|
Conjugation
|
|
|
Immunogen
|
|
|
Contents
|
Description:Summary: | Species: | Mu | | Applications: | WB, FACS | | Clonality: | Monoclonal | | | Gene: | ABCA7 | | Purity: | protein G purified | | Host: | Rat | | | Specificity: | This is specific for ABCA7. | Details: | Conjugate: | DyLight 488 | | Clone: | 7A1-144 | | Isotype: | IgG2a Kappa | | Immunogen: | Mouse ABCA7 stably-transfected HeLa cells. | | Epitope: | Extracellular determinants on ABCA7 of an unknown po sition. | | Localization: | Cell Membrane and Cytoplasmic | Gene Symbol: ABCA7 | Entrez: | 10347 (Human) | | Related Genes: | ABCA1, ABCA4, APOA1, ABCA2, ABCG1, ABCA3, ABCC1, ABCA8, ABCG5, APP, ABCG2, ABCD3, ABCA12, ABCB1, ABCF1, ABCA5, ABCC4, ABCG4, ABCD1, ABCE1, ABCD4, RFC2, RFC1, ABCB4, PLTP, ABCF3, PPARG, ABCG8, SQLE, ATP6V0A1, RFC4, ABCA9, MVK, SREBF2, SREBF1, EXOSC10, HMHA1, CFTR, ABCF2, SPTLC1 | Background: ABCA7, an ATP-binding cassette, sub-family A (ABC1), member 7, is highly homologous to ABCA1 and mediates cellular cholesterol and phospholipid release by apolipoproteins. The ABCA7 gene is regulated by sterol in the opposite direction to ABCA1 through SRE/SREBP2. The expression of ABCA7 by this regulation is associated with phagocytic activity. As well, it binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells and may mediate cholesterol efflux. Species: Applications: | Uses: | By Western Blot a 240 kDa band is seen. NB 400-163 is not reactive in ELISA. | | Dilutions: | flow cytometry / FACS analysis 1:500 - 1:4000 , Western Blot 1:2000 | | Concentrations: | 1.3 mg/ml | | Conjugated Ab's: | 4 conjugated antibodies | Packaging: | Buffer: | 50mM sodium borate | | Storage: | Store at 4C. Do not freeze. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
|
|
|
|
