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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-350999 |
NBP1-19758 |
ABCG2 Antibody//Human/Rabbit |
1/EA |
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문의 |
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Subject
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ABCG2 Antibody |
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Description
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/ Human/Rabbit |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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IHC-P, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Hu | | Applications: | IHC, WB | | Clonality: | Polyclonal | | | Gene: | ABCG2 | | Purity: | Affinity purified | | Host: | Rabbit | | | Specificity: | ABCG2 (N338) detects endogenous levels of ABCG2 protein. | Details: Gene Symbol: ABCG2 | Entrez: | 9429 (Human) | | Related Genes: | ABCB1, ABCC1, ABCC2, MSH3, MDM4, TBC1D9, KLHL1, MARCKSL1, GPR177, MVP, BANF1, PGPEP1, ABCC3, ABCC4, EGFR, ABCC5, LRP1, PTPRA, RPSA, SLCO1B1, ABCB4, MTX1, ABCB11, CD34, CD9, CYP3A4, SLCO1A2, CKAP4, NR1I2, TP63, SLCO1B3, SLCO2B1, NES, GSTP1, UVRAG, RPE65, SLC22A1, TOP1, CFTR, KRT3 | Background: ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of proteins that catalyze the transport of molecules across extracellular and intracellular membranes through the energy of ATP hydrolysis. The ABC halftransporter, ABCG2, is also known as placenta-specific ABC transporter and breast cancer resistance protein (BCRP1). ABCG2 confers resistance for a variety of chemotherapeutic agents, including anthracyclines, mitoxantrone, bisantrene and topotecan. Under normal conditions, ABCG2 may serve a protective function by removing toxins from the cell, and plays an important role in regulating stem cell differentiation. ABCG2 is responsible for the side population (SP) phenotype and is widely expressed in a large variety of stem cells, making it an important stem cell marker. ABCG2 may have N-linked glycosylation and may dimerize in vivo. ABCG2 is abundantly expressed in placenta, liver, intestine and stem cells. Species: Applications: | Uses: | This antibody is useful for Western Blot and Immunohistochemistry. Western blot analysis of ABCG2 (N338) antibody in extracts from HT-29 cells. Immunohistochemistry analyzes of ABCG2 (N338) antibody in paraffin-embedded human brain tissue. | | Dilutions: | Western Blot 1:500-1:1000, immunohistochemistry 1:50-1:200, | | Concentrations: | 1.0 mg/ml | Packaging: | Buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. | | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | 15mM Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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