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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-351003 |
H00009429-M01 |
ABCG2 Antibody (1G1)//Human/Mouse |
1/EA |
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문의 |
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Subject
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ABCG2 Antibody (1G1) |
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Description
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/ Human/Mouse |
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Clonality
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Mono |
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Company
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Novus biologicals |
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Application
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ELISA, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Hu | | Applications: | ELISA, WB | | Clonality: | Monoclonal | | | Gene: | ABCG2 | | Purity: | IgG purified | | Host: | Mouse | | | Specificity: | ABCG2 - ATP-binding cassette, sub-family G (WHITE), member 2 (1G1) | Details: | Clone: | 1G1 | | Isotype: | IgG2a Kappa | | Immunogen: | ABCG2 (NP_004818, 156 a.a. ~ 266 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | | Epitope: | EKNERINRVIQELGLDKVADSKVGTQ FIRGVSGGERKRTSIGMELITDPSIL FLDEPTTGLDSSTANAVLLLLKRMSK QGRTIIFSIHQPRYSIFKLFDSLTLL ASGRLM* | Gene Symbol: ABCG2 | Entrez: | 9429 (Human) | | Swiss Prot: | NP_004818 (Human) | | Related Genes: | ABCB1, ABCC1, ABCC2, MSH3, MDM4, TBC1D9, KLHL1, MARCKSL1, GPR177, MVP, BANF1, PGPEP1, ABCC3, ABCC4, EGFR, ABCC5, LRP1, PTPRA, RPSA, SLCO1B1, ABCB4, MTX1, ABCB11, CD34, CD9, CYP3A4, SLCO1A2, CKAP4, NR1I2, TP63, SLCO1B3, SLCO2B1, NES, GSTP1, UVRAG, RPE65, SLC22A1, TOP1, CFTR, KRT3 | Background: The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. [provided by RefSeq] Species: Applications: | Uses: | Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control. | | Dilutions: | Western Blot 1:500,ELISA | Notes: This product is produced by and distributed for Abnova, a company based in Taiwan. Packaging: | Buffer: | In 1x PBS, pH 7.2 | | Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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