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| Cat. No |
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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-351004 |
NB110-93511 |
ABCG2 Antibody (MM0047-2J39)//Human/Mouse |
1/EA |
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문의 |
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Subject
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ABCG2 Antibody (MM0047-2J39) |
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Description
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/ Human/Mouse |
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Clonality
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Mono |
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Company
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Novus biologicals |
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Application
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FACS, IHC-P, IHC-P |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Hu | | Applications: | IHC-P, IHC, FACS | | Clonality: | Monoclonal | | | Gene: | ABCG2 | | Purity: | protein G purified | | Host: | Mouse | | | Specificity: | This was selected for its ability to detect human ABCG2 by flow cytometry and immunocytochemistry. | Details: | Clone: | MM0047-2J39 | | Isotype: | IgG2 | | Immunogen: | human recombinant rHABCG2 protein | Gene Symbol: ABCG2 | Entrez: | 9429 (Human) | | Related Genes: | ABCB1, ABCC1, ABCC2, MSH3, MDM4, TBC1D9, KLHL1, MARCKSL1, GPR177, MVP, BANF1, PGPEP1, ABCC3, ABCC4, EGFR, ABCC5, LRP1, PTPRA, RPSA, SLCO1B1, ABCB4, MTX1, ABCB11, CD34, CD9, CYP3A4, SLCO1A2, CKAP4, NR1I2, TP63, SLCO1B3, SLCO2B1, NES, GSTP1, UVRAG, RPE65, SLC22A1, TOP1, CFTR, KRT3 | Background: An ABC transporter. Allows efflux of Hoechst dye, a property that has been used to separate bone marrow side population cells, which express BCRP/ABCG2. Appears to play a major role in the multidrug resistance phenotype of a specific MCF-7 breast cancer cell line. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123. Species: Applications: | Uses: | Flow cytometry / FACS analysis and Immunohistochemistry-Paraffin | | Dilutions: | flow cytometry / FACS analysis 1:100-1000, immunohistochemistry 1:100-1000, Immunohistochemistry-Paraffin 1:100-1000 | | Positive Controls: | 1 positive controls | Packaging: | Buffer: | PBS - lyophilized | | Storage: | Store at -20C. Avoid freeze-thaw cycles. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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