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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-351015 |
NBP1-05000 |
Abeta 40 Antibody//WB/Rabbit |
1/EA |
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문의 |
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Subject
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Abeta 40 Antibody |
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Description
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/ WB/Rabbit |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Applications: | WB | | Clonality: | Polyclonal | | | Gene: | APP | | Purity: | Affinity purified | | Host: | Rabbit | | | Specificity: | Amyloid beta (1-40) | | Publications: | Antibody has not yet been mentioned in a publication. | Details: | Immunogen: | This polyclonal antibody was raised by immunizing rabbit with a synthetic peptide containing 1-40 amino acids of amyloid. | Gene Symbol: APP | Related Genes: | BACE1, PSEN1, MAPT, APOE, ATP6V0A1, RFC1, RFC2, RFC4, ATP6V0A2, C21orf2, GPHA2, SGCA, ACHE, CD19, PRNP, LAMC2, CASP3, PSEN2, IDE, MME, SNCA, TG, TNF, CA1, MAPK1, INS, NOTCH, C4A, CAT, AKT1, GFAP, BDNF, NOS2, TFF1, BBS9, NFKB1, LTA4H, ALOX5, TWF1, PKC | Background: The amyloid beta (1-40) peptide (A beta) is the main component of amyloid deposits found in the brain of patients afflicted with Alzheimer's disease. Brain to blood transport is believed to be a major determinant of the amount of amyloid beta protein (AbetaP) found in brain. Chronic brain hypoperfusion (CBH) initiates spatial memory loss in aging rats thus mimicking human mild cognitive impairment (MCI) and also increases A beta 1-40 in the hippocampus. The memory and amyloid changes are preceded by NO upregulation in the hippocampus. These preliminary findings may be important in understanding, at least in part, the molecular mechanisms that precede memory impairment during chronic brain ischemia and as such, the pre-clinical stage leading to Alzheimer's disease. Species: Applications: | Uses: | The antibody titer is more than 10K for Dot blot and 1,000X for Western blot analysis. It has not been tested in the other applications. However, for the first testing, we recommend 1/5,000 dilution for ELISA, 1/1,000 dilution for Western blot analysis (WB) of recombinant protein, 1/400 dilution for tissue extracts or cell lysates, 1/100 dilution for immunohistochemistry (IHC) staining on frozen cryosections, 1/50 dilution for IHC staining on paraffin embedded sections. | | Dilutions: | Western Blot | Packaging: | Buffer: | lyophilized | | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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