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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-351079 |
NBP1-20093 |
ACCN1 Antibody//Human, Mouse,/Rabbit |
1/EA |
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문의 |
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Subject
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ACCN1 Antibody |
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Description
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/ Human, Mouse,/Rabbit |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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IHC-P, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Mu, Rt, Hu | | Applications: | WB, IHC | | Clonality: | Polyclonal | | | Gene: | ACCN1 | | Purity: | Whole antisera | | Host: | Rabbit | | | Specificity: | ACCN1. | | Publications: | Antibody has not yet been mentioned in a publication. | Details: | Immunogen: | A synthetic peptide from the extracellular domain of mouse amiloride sensitive cation channel 1, neuronal (ACCN1, ASIC2) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in human and rat. | Gene Symbol: ACCN1 | Entrez: | 40 (Human) | | | 11418 (Mouse) | | | 25364 (Rat) | | Swiss Prot: | Q925H0, Q16515, Q62962 (Human) | | Related Genes: | ACCN2, ACCN3, PICK1, ACCN4, DRG, BNC1, BDNF, STOM, HSPA8, FMR1, BNC2, MDEG1, PSD-95, STX1A, LTK, TNFRSF11A, CFTR, SCNN1B, SCNN1D, TRPV1, NTRK1, ACCN5, MSX1, NT-4, MYF5, FBLN2, THRB, KLKB1, CALR, GSTP1, GJB2, NPVF, MPO, CEACAM5, UBTF, SLC10A7, EXOSC2, PSG2, EIF2C2, PSG1 | Background: FUNCTION: Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate.; SUBUNIT: Homotetramer or heterotetramer with other ASIC proteins. Interacts with STOM. Interacts with PRKCABP and ACCN3.; SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Note: Localized at the plasma membrane of neurons, in the soma and punctated peripheral processes. Species: | Reactivity: | Human, rat, mouse. | Applications: | Uses: | Immunohistochemistry and Western Blot | | Dilutions: | immunohistochemistry,Western Blot 1:300 to 1:2000, | Notes: Reconstitute in 0.1 ml of sterile water. Centrifuge to remove any insoluble material. When reconstituting, glycerol (1:1) may be added for an additional stability. Packaging: | Buffer: | Lyophilized | | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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