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Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-23-351087 |
NBP1-05146 |
Acetylcholinesterase Antibody//Bovine, Human/Mouse |
1/EA |
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Subject
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Acetylcholinesterase Antibody |
Description
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/ Bovine, Human/Mouse |
Clonality
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Mono |
Company
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Novus biologicals |
Application
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ELISA, Western Blot |
Conjugation
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Immunogen
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Contents
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Description:Summary: Species: | Hu, Bv | Applications: | WB, ELISA | Clonality: | Monoclonal | | Gene: | ACHE | Purity: | protein A purified | Host: | Mouse | | Specificity: | Specific for brain AChE and does not recognize AChE from erythrocytes. The can thus distinguish between mammalian brain AChE and erythrocyte AChE. Weak cross-reactivity with Torpedo marmorata AChE but none with AChE from electric eel or human BtChE. | Publications: | Antibody has not yet been mentioned in a publication. | Details: Isotype: | IgG1 Kappa | Immunogen: | C-terminal 10 residues of brain acetylcholinesterase (human and bovine), absent from the erythrocyte enzyme. | Epitope: | C-terminal 10 residues (aa 574-583) of brain acetylc holinesterase (DS-AChE and SS-AChE) (1). | Gene Symbol: ACHE Entrez: | 43 (Human) | Related Genes: | CHAT, BCHE, CAT, SH2D3C, GLYAT, OP, VIP, TH, TAC1, NGF, G4, NPY, AFP, APP, PNPLA6, ACHR, ACE, DLD, GSTP1, LAMC2, GSTK1, SLCO6A1, SST, CA1, ALB, SLC18A3, NT5E, GFAP, BDNF, POMC, CA3, TRIM26, SOD1, LIPG, CALCA, CHRNA4, A12, S100A12, GPI, GSR | Background: Acetylcholinesterase (AChE, EC.3.1.1.7.) is an enzyme located in the postsynaptic membrane and in the muscle endplates, where it hydrolyses the neurotransmitter acetylcholin. AChE from brain is a tetramer (G4-AChE) with a molecular mass of 320 kDa, AChE from erythrocytes is a dimer (G2-AChE) with a molecular mass of 170 kDa. Detection of higher levels of AChE in amniotic fluid can indicate fetal malformations such as neural tube defects. Species: Reactivity: | Human and Bovine. | Applications: Uses: | ELISA and Western Blot | Dilutions: | ELISA 1:16000, Western Blot 1:75, | Concentrations: | 1.0 mg/ml | Packaging: Buffer: | 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl | Storage: | Store at 4C. Do not freeze. | Preservative: | 15mM Sodium Azide | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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