|
|
Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-23-351102 |
H00029974-B01P |
ACF Antibody//Human/Mouse |
1/EA |
|
|
|
|
¹®ÀÇ |
|
|
|
|
|
|
Subject
|
ACF Antibody |
Description
|
/ Human/Mouse |
Clonality
|
Poly |
Company
|
Novus biologicals |
Application
|
ELISA, Western Blot |
Conjugation
|
|
Immunogen
|
|
Contents
|
Description:Summary: Protein Type: | Full length Protein | Species: | Hu | Applications: | ELISA, WB | Clonality: | Polyclonal | | Gene: | A1CF | Purity: | protein A purified | Host: | Mouse | | Specificity: | A1CF - APOBEC1 complementation factor, | Details: Immunogen: | A1CF (NP_620311.1, 1 a.a. ~ 594 a.a) full-length human protein. | Epitope: | MEAVCLGTCPEPEASMSTAIPGLKKG NNALQSIILQTLLEKENGQRKYGGPP PGWDAAPPERGCEIFIGKLPRDLFED ELIPLCEKIGKIYEMRMMMDFNGNNR GYAFVTFSNKVEAKNAIKQLNNYEIR NGRLLGVCASVDNCRLFVGGIPKTKK REEILSEMKKVTEGVVDVIVYPSAAD KTKNRGFAFVEYESHRAAAMARRKLL PGRIQLWGHGIAVDWAEPEVEVDEDT MSSVKILYVRNLMLSTSEEMI | Gene Symbol: A1CF Entrez: | 29974 (Human) | Swiss Prot: | NP_620311.1 (Human) | Related Genes: | COL2A1, PCNA, CTNNB1, APOBEC1, PTGS2, APOBEC3B, CDA, APC, APOB, APOBEC4, GSTP1, NOS2, HRAS, SMARCA1, PROC, ISYNA1, BAZ1A, GSTK1, SLCO6A1, SMARCA5, TP53, INS, CAT, PPARG, CDKN1A, SYNCRIP, CCND1, DST, SLC25A21, MUC3A, IL8, ODC1, EGFR, NANOS2, MLH1, JUN, GLYAT, CASP3, CDKN2A, ALB | Background: Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined. [provided by RefSeq] Species: Applications: Uses: | Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control. | Dilutions: | Western Blot 1:500,ELISA | Notes: This product is produced by and distributed for Abnova, a company based in Taiwan. Packaging: Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. | Preservative: | No Preservative | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
|
|
|
|