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| Cat. No |
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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-351115 |
NB100-94233 |
Acinus Antibody//Human, Mouse/Rabbit |
1/EA |
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문의 |
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Subject
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Acinus Antibody |
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Description
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/ Human, Mouse/Rabbit |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Mu, Hu | | Applications: | WB | | Clonality: | Polyclonal | | | Gene: | ACIN1 | | Purity: | IgG purified | | Host: | Rabbit | | | Specificity: | Acinus | | Publications: | Antibody has not yet been mentioned in a publication. | Details: | Isotype: | IgG | | Immunogen: | Rabbit anti-Acinus (CP) polyclonal antibody was raised against a peptide (TRTALHGVKWPQSNPK) corresponding to amino acids 1065 to 1080 of human AcinusL, 338 to 353 of human AcinusS | Gene Symbol: ACIN1 | Entrez: | 22985 (Human) | | Related Genes: | NF2, CAT, ALB, EGF, PRDM10, GLUL, CCK, BBS9, CE, GLYAT, GSTP1, INS, PPA1, RRM2, CD1E, CD82, CYCS, PCNA, CASP3, AVP, CDKN1A, PI3, SOD1, AQP5, AKT1, ME1, G6PD, AKR1A1, PCNT, SERPINF2, PLEC1, RP, GGT1, GCG, PCK2, CREB3L1, ME3, ME2, TNF, TP53 | Background: Chromatin condensation and nuclear fragmentation (CCNF) is the hallmark of apoptosis. CCNF is triggered by the activation of members of caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE (1). A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus). Acinus is cleaved by caspase-3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse and designated AcinusL, AcinusS and AcinusS' (2). Species: | Reactivity: | This antibody is reactive against Human, Mouse | Applications: | Uses: | This polyclonal antibody can be used for detection of Acinus by Western blot at 0.5 to 1 ug/ml. K562 cell lysate can be used as positive control and an approximate 220 kDa band can be detected. | | Dilutions: | Western Blot 0.5-1 ug/ml, | Packaging: | Buffer: | Supplied in PBS | | Storage: | Store at 4C. Do not freeze. | | Preservative: | 0.02% Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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