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Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-23-356259 |
NBP1-19500 |
c Abl Antibody//Human, Mouse,/Rabbit |
1/EA |
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¹®ÀÇ |
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Subject
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c Abl Antibody |
Description
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/ Human, Mouse,/Rabbit |
Clonality
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Poly |
Company
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Novus biologicals |
Application
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IHC-P, Western Blot |
Conjugation
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Immunogen
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Contents
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Description:Summary: Species: | Rt, Mu, Hu | Applications: | IHC, WB | Clonality: | Polyclonal | | Gene: | ABL1 | Purity: | Affinity purified | Host: | Rabbit | | Specificity: | Abl (A198) detects endogenous levels of Abl protein. | Details: Gene Symbol: ABL1 Entrez: | 25 (Human) | | 11350 (Mouse) | | 311860 (Rat) | Related Genes: | BCR, MTTP, ITGB2, SRC, ITGAL, TP53, ITGAM, MYC, ETV6, CD34, IL3, AKT1, CNTNAP1, KIT, PIK3CG, RUNX1, JAK2, LTBR, CDKN2A, EGFR, BCL2, ITGAX, MLL, BCL2L1, MAPK1, STAT5A, STAT5B, KITLG, PDGFRB, IL2, CDKN1A, PTK2B, EGF, ABI1, GRB2, NOL3, CRK, CR3, JUN, FOS | Background: The c Abl proto oncogene encodes a protein tyrosine kinase that is located in the cytoplasm and nucleus. In chronic myelogenous leukemia and in a subset of acute lymphoblastic leukemias, the c Abl proto oncogene undergoes a (9;22) chromosomal translocation producing a novel rearranged chromosome (the Philadelphia chromosome) As the result of the fusion of c Abl sequences from chromosome 9 to the Bcr gene on chromosome 22. The molecular consequence of this translocation is the generation of a chimeric Bcr/Abl mRNA encoding activated Abl protein tyrosine kinase. Species: Reactivity: | Human, Mouse, Rat | Applications: Uses: | This antibody is useful for Western Blot and Immunohistochemistry.Western blot analysis of Abl (A198) antibody in extracts from COS7 cells. | Dilutions: | Western Blot 1:500-1:1000,immunohistochemistry 1:50-1:200, | Packaging: Buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | Preservative: | No Preservative | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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