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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-351241 |
H00000835-M10 |
active Caspase 2 Antibody (1C11)//Human/Mouse |
1/EA |
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문의 |
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Subject
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active Caspase 2 Antibody (1C11) |
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Description
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/ Human/Mouse |
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Clonality
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Mono |
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Company
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Novus biologicals |
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Application
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ELISA, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Hu | | Applications: | WB, ELISA | | Clonality: | Monoclonal | | | Gene: | CASP2 | | Purity: | IgG purified | | Host: | Mouse | | | Specificity: | CASP2 - caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | Details: | Clone: | 1C11 | | Isotype: | IgG2a Kappa | | Immunogen: | CASP2 (AAH02427, 121 a.a. ~ 220 a.a) partial recombinant protein with GST tag. | | Epitope: | TLSGLQHVLPPLSCDYDLSLPFPVCE SCPLYKKLRLSTDTVEHSLDNKDGPL CLQVKPCTPEFYQTHFQLAYRLQSRP RGLALVLSNVHFTGEKELEFRS | Gene Symbol: CASP2 | Entrez: | 835 (Human) | | Omim: | 600639, (Human) | | Swiss Prot: | AAH02427 (Human) | | Related Genes: | CASP3, CASP9, CASP8, CASP1, CYCS, BCL2L1, BCL2, CASP7, BAX, PARP1, BID, CASP6, CRADD, FAS, TP53, ICH-1, LRDD, COL11A2, APAF1, FASLG, DIABLO, BAK1, FADD, TNFSF10, AIFM1, MAPK8, TNF, CDKN1A, CUX1, CASP10, MCL1, CRTAP, CYTIP, NFKB1, GZMB, RIPK1, AKT1, XIAP, JUN, HTT | Background: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. Species: | Reactivity: | Human. Other species not tested. | Applications: | Uses: | Antibody Reactive against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control. | | Dilutions: | ELISA,Western Blot 1:500 | Notes: This product is produced by and distributed for Abnova, a company based in Taiwan. Packaging: | Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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