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Description |
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Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-351377 |
H00000093-B01 |
Activin Receptor Type IIB Antibody//Human/Mouse |
1/EA |
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문의 |
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Subject
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Activin Receptor Type IIB Antibody |
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Description
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/ Human/Mouse |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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ELISA, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Protein Type: | Full length Protein | | Species: | Hu | | Applications: | ELISA, WB | | Clonality: | Polyclonal | | | Gene: | ACVR2B | | Purity: | Whole antisera | | Host: | Mouse | | | Specificity: | ACVR2B - activin A receptor, type IIB, | Details: | Immunogen: | ACVR2B (AAH96245.1, 1 a.a. ~ 303 a.a) full-length human protein. | | Epitope: | MNDFVAVKIFPLQDKQSWQSEREIFS TPGMKHENLLQFIAAEKRGSNLEVEL WLITAFHDKGSLTDYLKGNIITWNEL CHVAETMSRGLSYLHEDVPWCRGEGH KPSIAHRDFKSKNVLLKSDLTAVLAD FGLAVRFEPGKPPGDTHGQVGTRRYM APEVLEGAINFQRDAFLRIDMYAMGL VLWELVSRCKAADGPVDEYMLPFEEE IGQHPSLEELQEVVVHKKMRPTIKDH WLKHPGLAQLCVTIEECWDHD | Gene Symbol: ACVR2B | Entrez: | 93 (Human) | | Swiss Prot: | AAH96245.1 (Human) | | Related Genes: | ACVR2A, MSTN, ACVR1B, BMP7, ACVR1, FST, BMP2, BMP4, BMPR2, SMAD2, NODAL, TGFBR3, BMPR1B, TGFB1, BMPR1A, BMP6, TDGF1, SMAD4, BMPRII, BMP-2, EGF, BRD2, BMP-7, GARS, SMAD1, SMAD3, GDF11, BMPR-IA, LEFTY2, CDKN1A, ACVRL1, BMPR-IB, TGFBR1, ZIC3, BMP3, MAPK3, SMAD7, ACVR1C, TGFB3, SYNJ2BP | Background: Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. [provided by RefSeq] Species: Applications: | Uses: | Antibody reactive against transfected lysate for western blot. It has also been used for ELISA. | | Dilutions: | Western Blot 1:500,ELISA | Notes: This product is produced by and distributed for Abnova, a company based in Taiwan. Packaging: | Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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