| Synonyms | H2Qa2 |
| Immunogen | C3H.SW mouse skin graft and splenocytes. (Ref.1) |
| Product Type | Antibodies |
| Recommended Isotype Control | AM03096PU-N |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. Sharrow, S.O., J.S. Arn, I. Stroynowski, L. Hood, and D.H. Sachs. 1989. J. Immunol. 142:3495-3502. 2. Sharabi, Y., and D.H. Sachs. 1990. J. Exp. Med. 171:211-219. |
|
| Format | State: Liquid purified Ig fraction. |
| ? | Buffer System: 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added. |
|
| Specificity | This antibody recognises Qa-2 alloantigen. It reacts with a Qa-2-determined alloantigen. |
| Application | Flow Cytometry: < / = 1 µg/10e6 cells. Complement-mediated cytotoxicity Modulation of Qa-2 expression from peripheral T lymphocytesa. (Ref.2) |
| Background | Qa antigens are 'non classical' MHC class I molecules of mice. Qa2 is present on restricted functional lymphocyte subpopulations. The protein product of the preimplantation embryo development (Ped) gene, Qa2 influences the rate of embryonic cleavage during the preimplantation stages of development. |
| Concentration | 0.5 mg/ml |
