| Synonyms | Glutaminyl-tRNA synthetase; Glutamine--tRNA ligase; GlnRS; QARS |
| Swiss Prot Num | P47897 |
| Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human QARS. |
| Product Type | Antibodies |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. Ko,Y.G., J. Biol. Chem. 276 (8), 6030-6036 (2001) 2. Kang,J., J. Biol. Chem. 275 (41), 31682-31688 (2000) 3. Ko,Y.G., J. Cell Biol. 149 (3), 567-574 (2000) |
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| Format | State: Liquid purified Ig |
| ? | Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS |
| ? | Buffer System: PBS with 0.09% (W/V) sodium azide |
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| Specificity | This antibody reacts to QARS. |
| Application | ELISA: 1/1,000. Immunohistochemistry: 1/10 - 1/50. |
| Background | Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family. |
| Caution | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Concentration | 0.25 mg/ml |
