| Synonyms | RAB5A, RAB5, Ras-related protein Rab-5A |
| Swiss Prot Num | P20339 |
| Immunogen | Recombinant human Rab5a (1-215 aa) purified from E. coli |
| Product Type | Antibodies |
| Recommended Isotype Control | SM12P, AM03110PU-N |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | Tan BK, et al. (2007) J Clin Endocrinol Metab. 92(7):2590-7. Yao Borengasser A, et al. (2007) J Clin Endocrinol Metab. 92(7):2430-2. |
|
| Format | State: Liquid purified Ig fraction |
| ? | Purification: Protein G affinity chromatography |
| ? | Buffer System: PBS, pH 7.4, containing 0.09% sodium azide |
|
| Specificity | The antibody recognizes human and mouse RAB5A. Other species not tested. |
| Application | ELISA. Western blot (1:500 - 1:2,000). |
| Background | Rab5a is a member of the RAS oncogene family. Rab5a is a small GTPase localized to the plasma membrane and early endosomes. It is a crucial regulatory component of the endocytic pathway. Activation of Rab5a is mediated by GDP-GTP exchange factors (GEFs) that generate the Rab5-GTP complex. |
| Concentration | 1.0 mg/ml |
