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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-351597 |
NBP1-19546 |
Adenosine Kinase Antibody//Human, Mouse,/Rabbit |
1/EA |
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문의 |
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Subject
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Adenosine Kinase Antibody |
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Description
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/ Human, Mouse,/Rabbit |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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IF, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Rt, Mu, Hu | | Applications: | IF, WB | | Clonality: | Polyclonal | | | Gene: | ADK | | Purity: | Affinity purified | | Host: | Rabbit | | | Specificity: | ADK (E6) detects endogenous levels of ADK protein. | Details: Gene Symbol: ADK | Entrez: | 132 (Human) | | | 11534 (Mouse) | | | 25368 (Rat) | | Related Genes: | ADA, APRT, ADO, PNP, AHCY, DCK, NT5E, HPRT1, PGD, RFC1, ATP6V0A1, RFC2, RFC4, PPY, AK1, XDH, RBKS, GPI, PGM1, IL2, ADORA1, A4GALT, ADORA2A, AK2, INS, ATIC, SERPINB3, HP, SLC29A1, SGCA, C21orf2, CAT, GPHA2, ATP6V0A2, G6PD, C6, PSMA7, TNF, DGUOK, PRKAA2 | Background: Adenosine kinase (ATP:adenosine 5 prime phosphotransferase) is an abundant enzyme in mammalian tissues that catalyzes the transfer of the gamma phosphate from ATP to adenosine, thereby serving as a potentially important regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of ADK could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as antiinflammatory agents. The encoded protein does not present any sequence similarities to other well characterized mammalian nucleoside kinases. In contrast, 2 regions were identified with significant sequence identity to microbial ribokinase and fructokinases and a bacterial inosine/guanosine kinase. Thus, ADK is a structurally distinct mammalian nucleoside kinase that appears to be akin to sugar kinases of microbial origin. Species: | Reactivity: | Human, Mouse, Rat | Applications: | Uses: | This antibody is useful for Western Blot and Immunofluorescence.Western blot analysis of ADK (E6) antibody in extracts from RAW264.7 cells. | | Dilutions: | Western Blot 1:500-1:1000 ,immunofluorescence 1:50-1:200, | Packaging: | Buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. | | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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