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Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-24-67611 |
SM2099LE |
Hamster Anti-CD49a (Integrin alpha 1 chain) Monoclonal Antibody, Unconjugated, Clone HMalpha1/0.5 mg/Mouse/Hamster |
1/EA |
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Subject
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Hamster Anti-CD49a (Integrin alpha 1 chain) Monoclonal Antibody, Unconjugated, Clone HMalpha1 |
Description
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0.5 mg / Mouse/Hamster |
Clonality
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Mono |
Company
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Acris Antibodies GmbH |
Application
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Flow cytometry, Functional assay, Immunoprecipitation |
Conjugation
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Unconjugated |
Immunogen
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CD49a (Integrin alpha 1 chain), Integrin alpha1 |
Contents
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Description: Manufacturer | Acris Antibodies GmbH | Quantity | 0.5 mg | Reactivity | Mouse | Presentation | Low Endotoxin | Applications | Flow cytometry, Functional assay, Immunoprecipitation | Isotype | IgG | Host | Hamster | Clone | HMalpha1 | PDF datasheet | view | Shipping to | Worldwide | Synonyms | Integrin alpha-1, ITGA1, VLA-1 | Swiss Prot Num | Q3V3R4 | Immunogen | C1300 mouse neuroblastoma cell line. Spleen cells from immunised Armenian Hamsters were fused with cells of the mouse P3U1 mouse myeloma cell line. | Product Type | Antibodies | Storage | Store the antibody at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch. | References | 1. Miyake, S. et al. (1994) Indentification of collagen and laminin receptor integrins on murine T lymphocytes. Eur. J. Immunol. 24: 2000-2005. | |
Format | State: Liquid purified IgG | ? | Purification: Affinity chromatography on Protein G | ? | Buffer System: PBS, pH7.4 | |
Specificity | This antibody recognises alpha 1 integrin (CD49a). Clone HM alpha 1 is reported to block VLA-1 dependent adhesion. | Application | Flow Cytometry: 1/25- 1/100; use 10 ?l of the suggested working dilution to label 106 cells in 100ul. Immunoprecipitation. Functional assays. | Background | CD49a is a 180kD transmembrane glycoprotein, which associates with the beta 1 intergrin subunit to form the CD49a/CD29 (VLA-1) heterodimer. CD49a is expressed on activated T lymphocytes and at low levels on monocytes. VLA-1 is a receptor for laminin and collagen and plays an important role in regulating adhesion. | Concentration | 1.0 mg/ml | |
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