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Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-24-58425 |
SM2246P |
Hamster Anti-CD121a (IL-1 Receptor I) Monoclonal Antibody, Unconjugated, Clone JAMA-147/0.25 mg/Mouse/Hamster |
1/EA |
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Subject
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Hamster Anti-CD121a (IL-1 Receptor I) Monoclonal Antibody, Unconjugated, Clone JAMA-147 |
Description
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0.25 mg / Mouse/Hamster |
Clonality
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Mono |
Company
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Acris Antibodies GmbH |
Application
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Flow cytometry, Immunoprecipitation |
Conjugation
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Unconjugated |
Immunogen
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CD121a (IL-1 Receptor I), IL1 |
Contents
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Description: Manufacturer | Acris Antibodies GmbH | Quantity | 0.25 mg | Reactivity | Mouse | Presentation | Purified | Applications | Flow cytometry, Immunoprecipitation | Isotype | IgG | Host | Hamster | Clone | JAMA-147 | PDF datasheet | view | Shipping to | Worldwide | Synonyms | Interleukin-1 receptor type I, IL-1R-1, IL-1RT1, IL-1R-alpha, p80, IL1RA, IL1RT1 | Swiss Prot Num | P13504 | Immunogen | Extracellular domain of murine IL-1R. Spleen cells from immunised Armenian Hamster were fused with cells of the mouse P3X63.Ag 8-653 myeloma cell line. | Product Type | Antibodies | Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. | References | 1. Rogers, H. W. et al. (1992) Interleukin 1 participates in the development of anti-Listeria responses in normal and SCID mice. Proc. Natl. Acad. Sci. USA. 89:1011-1015. | |
Format | State: Liquid purified IgG | ? | Purification: Affinity chromatography on Protein G | ? | Buffer System: PBS, pH7.4 containing 0.09% Sodium Azide | |
Specificity | This antibody recognises CD121a, which is the 80kD type I interleukin-1 receptor. Clone JAMA-147 has been reported to block IL-1 dependent cellular responses. | Application | Flow Cytometry: 1/25 - 1/100; Use 10?l of the suggested working dilution to label 10e6 cells in 100?l. Immunoprecipiation. | Background | CD121a is weakly expressed on most cells and tissues including T lymphocytes, thymocytes, epithelial cells and dendritic cells, with stronger expression reported on fibroblasts. The ligands for CD121a are the interleukin-1 (IL-1) family members; IL-1 alpha; IL-1 beta and IL-1 receptor antagonist. IL-1 is a mediator of inflammation and can elicit a variety of other biological responses through binding to CD121a. | Concentration | 1.0 mg/ml | |
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