|
|
Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-24-35902 |
SM5140 |
Hamster Anti-bcl-3 Monoclonal Antibody, Unconjugated, Clone Ham150-3.5/0.1 mg/Human, Mouse/Hamster |
1/EA |
|
|
|
|
¹®ÀÇ |
|
|
|
|
|
|
Subject
|
Hamster Anti-bcl-3 Monoclonal Antibody, Unconjugated, Clone Ham150-3.5 |
Description
|
0.1 mg / Human, Mouse/Hamster |
Clonality
|
Mono |
Company
|
Acris Antibodies GmbH |
Application
|
Enzyme Immunoassay, Western blot / Immunoblot |
Conjugation
|
Unconjugated |
Immunogen
|
bcl-3, bcl3 |
Contents
|
Description: Manufacturer | Acris Antibodies GmbH | Quantity | 0.1 mg | Reactivity | Human, Mouse | Presentation | Purified | Applications | Enzyme Immunoassay, Western blot / Immunoblot | Isotype | IgG1 | Host | Hamster | Clone | Ham150-3.5 | Shipping to | Worldwide | Synonyms | BCL3, BCL4, D19S37 | Swiss Prot Num | P20749 | Immunogen | Full length mouse Bcl-3 protein. | Product Type | Antibodies | Storage | Store the antibody at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch. | |
Format | State: Liquid purified IgG fraction. | ? | Purification: Protein G chromatography. | ? | Buffer System: PBS with 1 mg/ml BSA and 0.05% sodium azide as preservative. | |
Specificity | SM5140 detects human and mouse Bcl-3 from transfected cells and shows no cross-reactivity to other Bcl isoforms. | Application | ELISA. Western Blot: 2 ?g/ml, detects an ~47 kDa protein representing Bcl-3 from C57BI/6 human T cells and Bcl-3 transgenic ms T cells. | Background | B cell Lymphoma 3 is a member of the IkB subfamily of inhibitors. This subfamily is part of the NF-kB transcription factor protein family and it is suggested that a balance in the concentration of various NF-kB family members regulates apoptosis and survival of activated T cells. Bcl-3 has been shown to have versatile functions such as cytoplasmic activation of p50 homodimers, translocation to the nucleus, and modulation of the transcriptional machinery in the nucleus. Bcl-3 activity often relies on several nuclear interacting proteins such as Tip60, Jab1, Bard1, and Pirin. | Concentration | 1.0 mg/ml | |
|
|
|
|