SNPase is a Taq DNA Polymerase with N-terminal deletion and proprietary amino acid substitutions introduced into the active center of the enzyme. This modification causes dramatic increase of sensitivity of the enzyme to mismatches at 3¡¯-end of the primer. Consequently, non-perfect annealing of the primers does not result in unspecific amplicon formations. SNPase was recognized as one of the best Polymerases in SNP detection by allele-specific PCR and micro sequencing. ¡á Bioron